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  1. Cytotoxic T lymphocytes (CTL) protect against viruses including HIV-1. To avoid viral escape mutants that thwart immunity, we chose 25 CTL epitopes defined in the context of natural infection with functional a...

    Authors: Pedro A Reche, Derin B Keskin, Rebecca E Hussey, Petronela Ancuta, Dana Gabuzda and Ellis L Reinherz

    Citation: Medical Immunology 2006 5:1

    Content type: Research

    Published on:

  2. It has been more than 100 years since the realization that microbes are capable of causing disease. In that time, we have learned a great deal as to how each organism has adapted to the immune system so as to ...

    Authors: Kendall A Smith

    Citation: Medical Immunology 2005 4:5

    Content type: Editorial

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  3. Medical Immunology will be publishing invited Reviews and Commentaries from investigators who are at the forefront of their fields, to up-date our readers as to the current state of their art. These Reviews an...

    Authors: Kendall A Smith

    Citation: Medical Immunology 2005 4:3

    Content type: Editorial

    Published on:

  4. Eradication of the smallpox virus through extensive global vaccination efforts has resulted in one of the most important breakthroughs in medical history, saving countless lives from the severe morbidity and m...

    Authors: Mark K Slifka

    Citation: Medical Immunology 2005 4:2

    Content type: Commentary

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  5. FADD (Fas Associated protein with Death Domain) is a key adaptor molecule transmitting the death signal mediated by death receptors. In addition, this multiple functional protein is implicated in survival/prol...

    Authors: Léa Tourneur, Agnès Buzyn and Gilles Chiocchia

    Citation: Medical Immunology 2005 4:1

    Content type: Review

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  6. Conventional vaccines afford protection against infectious diseases by expanding existing pathogen-specific peripheral lymphocytes, both CD8 cytotoxic effector (CTL) and CD4 helper T cells. The latter induce B...

    Authors: Masha Fridkis-Hareli and Ellis L Reinherz

    Citation: Medical Immunology 2004 3:2

    Content type: Commentary

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  7. Members of the NF-kB transcription factor family are differentially expressed in the B cell lineage. Disruption of individual or two NF-kB subunits exhibits distinct defects in B lymphocyte development, activa...

    Authors: Biao Feng, Shuhua Cheng, Warren S Pear and Hsiou-Chi Liou

    Citation: Medical Immunology 2004 3:1

    Content type: Research

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  8. While the ability of bacteriophages to kill bacteria is well known and has been used in some centers to combat antibiotics – resistant infections, our knowledge about phage interactions with mammalian cells is...

    Authors: Andrzej Gorski, Krystyna Dabrowska, Kinga Switala-Jeleń, Maria Nowaczyk, Beata Weber-Dabrowska, Janusz Boratynski, Joanna Wietrzyk and Adam Opolski

    Citation: Medical Immunology 2003 2:2

    Content type: Hypothesis

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  9. The development of a vaccine that can prevent infection by the Human immunodeficiency virus or prevent the Acquired Immunodeficiency Syndrome has remained elusive despite 20 years of scientific effort. This "C...

    Authors: Kendall A Smith

    Citation: Medical Immunology 2003 2:1

    Content type: Commentary

    Published on:

  10. Long term treatment with immunosuppressive agents results in nephrotoxicity in renal transplant recipients. We explored the effect of combination of Tacrolimus (TAC) and Sirolimus (SRL) on the immune system in...

    Authors: Ashwani Khanna, Matthew Plummer, Katherine Bromberek, Jeffrey Woodliff and Sundaram Hariharan

    Citation: Medical Immunology 2002 1:3

    Content type: Research

    Published on:

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