Figure 2

IL-2-responsive probe sets in PBMCs and purified T cells. (A). Using the criterion of p < 0.05 for the difference between the means of IL-2-treated and untreated groups, a total of 316 IL-2-sensitive probe sets were identified in PBMCs (left circle), and 439 in purified T cells (right circle). Of these, 110 were identified in both cell populations (overlap between circles). (B). When a second standard of either fold change ≥ 2 or subtracted difference ≥ 100 was included in the analysis, 251 probe sets were identified in PBMCs, and 161 in pure T cells, with 71 in common. (C). When all three criteria were used, 84 probe sets were identified in PBMCs, 52 in T cells, and 23 of these were common to both populations. Within each population, the percentages of IL-2- suppressed and induced probe sets are indicated.